The aroma of breakfast wafting through the house can stir up the best memories, often involving family gatherings and lazy weekend mornings. My Hearty Biscuit Breakfast Casserole is a nostalgic tribute to those cherished moments, easily becoming the star of any brunch table. This crowd-pleaser combines fluffy biscuits, savory sausage, and gooey cheese into one warm and inviting casserole that is not just delicious but also incredibly easy to prepare. Whether you’re hosting a holiday feast or simply want to make weekend mornings special, it’s the ultimate make-ahead dish that will impress your friends and family. Plus, it’s versatile enough to fit a variety of tastes. Ready to dive into this savory delight? Let’s get cooking!

What makes this breakfast casserole special?
Ease of Preparation: This Hearty Biscuit Breakfast Casserole can be assembled in just a few simple steps, making it perfect for busy mornings.
Irresistible Flavor: Enjoy the savory richness of Italian sausage mingling perfectly with fluffy, buttery biscuits and melted cheese.
Make-Ahead Convenience: Easily prepare this casserole the night before; it’s just as delightful when baked fresh or reheated.
Crowd-Pleasing Dish: Perfect for family gatherings or holiday brunches, this dish brings everyone together for a warm, comforting meal.
Customizable Options: Switch up the sausage for bacon or add fresh veggies like spinach for extra nutrition — the possibilities are endless!
Elevate your breakfast game with this hearty masterpiece, and don’t forget to try it alongside some fresh fruit or a decadent Eggs Benedict Casserole for a complete brunch experience!
Biscuit Breakfast Casserole Ingredients
• Perfect for a hearty start!
For the Casserole
- Italian Ground Sausage – Adds savory flavor and protein; can substitute with turkey sausage for a leaner option.
- Canned Grand Biscuits – Forms the base and adds fluffiness; feel free to use homemade biscuits for an even fresher taste.
- Shredded Cheddar Cheese – Provides a sharp flavor; can be swapped with a cheese blend or Monterey Jack for variety.
- Shredded Mozzarella Cheese – Contributes creaminess and stretch; reduce quantity for a lighter finish.
- Large Eggs – Binds the ingredients and adds richness; use nutritional yeast for a vegan alternative.
- Milk – Adds moisture and creaminess; almond milk or a non-dairy alternative works well too.
- Salt (to taste) – Enhances overall flavor; adjust according to dietary needs.
- Black Pepper (to taste) – Adds a touch of spice; white pepper can be used for a different flavor twist.
Elevate your mornings with this delightful Biscuit Breakfast Casserole that everyone will love!
Step‑by‑Step Instructions for Hearty Biscuit Breakfast Casserole
Step 1: Preheat the Oven
Preheat your oven to 400°F (200°C) and prepare a 9×13 inch baking pan by greasing it with cooking spray or butter. This will ensure that your Hearty Biscuit Breakfast Casserole doesn’t stick and turns out beautifully golden brown. Take a moment to gather all your ingredients so they’re ready for the next steps.
Step 2: Cook the Sausage
In a large sauté pan, add the Italian ground sausage over medium heat. Use a spatula to break it into crumbles as it cooks, allowing it to brown evenly for about 5-7 minutes. Once fully cooked and browned, drain any excess grease from the sausage to keep your casserole rich but not greasy.
Step 3: Prepare the Biscuits
Open the canned Grand biscuits and cut each biscuit into eight equal pieces. This helps them to incorporate evenly into the casserole, creating delightful fluffy layers. Spread the biscuit pieces in a single layer across the bottom of your prepared baking pan, ensuring every corner is covered.
Step 4: Layer with Sausage and Cheese
Evenly distribute the cooked sausage over the layer of biscuits in the pan. Then, sprinkle half a cup of both shredded cheddar and mozzarella cheese on top of the sausage. This will create a savory, cheesy base that complements the biscuits perfectly in your Biscuit Breakfast Casserole.
Step 5: Mix the Egg Mixture
In a separate bowl, whisk together the large eggs, milk, salt, and black pepper until fully combined, creating a creamy mixture. This will add moisture and richness to your casserole. Pour this mixture evenly over the layered biscuits and sausage, ensuring every piece is soaked with that delectable egg goodness.
Step 6: Add the Remaining Cheese
Top your cascading Biscuit Breakfast Casserole with the remaining shredded cheddar and mozzarella cheese. This creates a deliciously gooey and golden crust once baked, enhancing the overall flavor and texture. Make sure to cover all layers with cheese for the ultimate cheesy experience!
Step 7: Bake to Perfection
Place your prepared casserole in the preheated oven and bake for 25-35 minutes. You’ll know it’s ready when the eggs are set in the center and the top is beautifully golden brown. Keep an eye on it during the last few minutes to achieve that perfect color.
Step 8: Cool and Serve
Once baked to perfection, remove the casserole from the oven and let it sit for about 5 minutes. This resting time allows the flavors to meld and helps with clean slicing. Use a sharp knife to cut portions and serve warm; your Hearty Biscuit Breakfast Casserole is now ready to be enjoyed!

How to Store and Freeze Biscuit Breakfast Casserole
Fridge: Store leftovers in an airtight container for up to 3-4 days. Reheat in the microwave or oven until heated through for a quick breakfast fix!
Freezer: You can freeze the unbaked casserole for up to 2 months. Just cover it tightly with foil and wrap in plastic wrap. Thaw overnight in the fridge before baking.
Reheating: For best results, reheat cooked portions in the oven at 350°F (175°C) for about 15-20 minutes, or microwave individual servings until warm.
Airtight Wrapping: Always ensure your Biscuit Breakfast Casserole is properly sealed to maintain freshness and prevent freezer burn.
Biscuit Breakfast Casserole Variations
Feel free to get creative and make this Biscuit Breakfast Casserole your own with these enjoyable twists!
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Swap Meats: Replace Italian sausage with bacon or diced ham for a smoky flavor variation. Each option brings its unique charm and richness to the casserole.
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Add Veggies: Toss in chopped bell peppers, spinach, or sautéed onions for a healthier touch. These veggies not only add nutrition but also a burst of color and texture.
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Cheese Twists: Use feta cheese for a tangy surprise, or a blend of cheeses for a more complex flavor. Combining different cheeses creates an unforgettable creamy experience.
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Spice it Up: If you’re craving heat, add diced jalapeños or a sprinkle of red pepper flakes. It offers a zesty kick that wakes up your taste buds!
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Gluten-Free: Substitute canned Grand biscuits with gluten-free biscuits for a delicious option suitable for everyone. Everyone deserves a seat at the brunch table!
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Herb Infusion: Fresh herbs like chives or parsley can elevate the flavor profile. Add them to the egg mixture for an aromatic boost that brightens every bite.
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Sweet Twist: For a unique take, drizzle maple syrup over individual servings. The sweet and savory combination is delightful and perfect for those who enjoy a surprise!
Feel like mixing things up? Or are you in the mood for something more savory? If you want to try a different kind of casserole, check out this Chicken Fajita Casserole or a creamy Egg Cheese Breakfast dish. The world of casseroles is a delightful journey filled with flavors!
Expert Tips for Biscuit Breakfast Casserole
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Assemble Ahead: Prepare your Biscuit Breakfast Casserole the night before and refrigerate it. Let it sit at room temperature for 15 minutes before baking for even cooking.
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Check for Doneness: Baking times may vary based on your oven; always check that the eggs are fully set in the center before removing it from the oven.
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Customize Wisely: If you swap meats or cheeses, adjust cooking times accordingly. For example, bacon or ham may require less cooking time than sausage.
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Perfect Portions: For neat slicing, allow the casserole to rest for a few minutes after baking; this helps it firm up and makes serving easier.
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Keep It Fresh: Leftovers store well! Keep your biscuit breakfast casserole wrapped in an airtight container in the fridge for 3-4 days; reheat as needed.
Make Ahead Options
Preparing your Hearty Biscuit Breakfast Casserole ahead of time is a fantastic way to save time on busy mornings! You can assemble the entire casserole up to 24 hours in advance by following the initial steps, then cover it tightly with plastic wrap and refrigerate. To ensure the best quality, let the casserole sit at room temperature for about 20 minutes before baking to take the chill off. When you’re ready to enjoy, simply pop it into the preheated oven (you may need to increase baking time by a few minutes) and bask in the delightful aroma filling your kitchen. With this make-ahead option, you’ll be savoring a delicious breakfast effortlessly, allowing you to focus on making memories with your loved ones!
What to Serve with Hearty Biscuit Breakfast Casserole
Bring the hustle and bustle of a cozy breakfast table to life with these delightful pairings!
- Fresh Fruit Salad: A vibrant mix of seasonal fruits adds a refreshing contrast to the rich casserole and brings color to your brunch spread.
- Crispy Bacon: The salty crunch of crispy bacon complements the fluffy, cheesy casserole perfectly, adding an irresistible flavor combo.
- Savory Coffee Cake: A slice of warm coffee cake offers a sweet finish that superbly balances the hearty, savory elements of the casserole.
- Roasted Veggies: Tossed with olive oil and herbs, roasted vegetables contribute nutritious and colorful elements, enhancing your breakfast experience.
- Iced Coffee or Mimosas: Brewed coffee served chilled or fizzy mimosas with orange juice provide a refreshing beverage option that pairs beautifully with the casserole.
- Greek Yogurt Parfait: Layered with granola and honey, a yogurt parfait introduces a creamy and sweet dimension, perfect for contrasting the casserole’s richness.
- Herbed Biscuits: For biscuit enthusiasts, opt for homemade herb-infused biscuits on the side for an added buttery, flaky texture that complements the dish.
- Green Salad with Vinaigrette: A light, dressed salad will bring balance to your plate, refreshing the palate between bites of the rich casserole.
- Chilled Fruit Smoothie: A creamy, delicious smoothie offers a nutritious option that cools down the meal while delivering a fruity punch.
- Apple Pie: For a touch of dessert, serving a slice of warm apple pie adds sweetness, turning breakfast into a true feast for the senses!

Biscuit Breakfast Casserole Recipe FAQs
How do I choose the right sausage for my casserole?
Absolutely! For your Biscuit Breakfast Casserole, fresh Italian ground sausage is the perfect choice, providing rich, savory flavors that harmonize beautifully with the other ingredients. If you’re looking for a leaner alternative, turkey sausage works just as well without sacrificing flavor. Look for sausage with a good fat content—around 20% is ideal—as it adds moisture and depth to the dish.
How should I store leftovers from my Biscuit Breakfast Casserole?
Very simple! Store any leftovers in an airtight container in the fridge for up to 3-4 days. Just make sure to let it cool first. When you’re ready to enjoy it again, you can easily reheat individual portions in the microwave or pop the casserole back into the oven until warmed through—this keeps the biscuits nice and fluffy!
Can I freeze the Biscuit Breakfast Casserole? What’s the best way to do it?
Absolutely! Freezing this delightful dish is a breeze. If you want to freeze the casserole before baking, simply cover it tightly with foil and plastic wrap. It can be stored in the freezer for up to 2 months. When you’re ready to bake it, thaw it overnight in the fridge before following the baking instructions. For best results, allow it to come to room temperature for about 15 minutes before placing it in the oven.
What should I do if my casserole isn’t baking evenly?
No worries; this can easily happen! Make sure your oven is properly preheated before placing your casserole inside. If you notice one side is cooking faster than the other, you may want to rotate the pan halfway through baking. Additionally, if the top is browning too quickly while the inside remains undone, you can loosely cover it with foil to prevent over-browning.
Can I make this casserole vegetarian-friendly?
Absolutely, it’s quite adaptable! To make your Biscuit Breakfast Casserole vegetarian, simply replace the Italian ground sausage with a mix of sautéed vegetables, like bell peppers, spinach, and mushrooms, or use meat substitutes such as tofu or tempeh. Just remember to season well, as the sausage provides a lot of flavor!
Can my pets enjoy leftovers from the casserole?
While it might be tempting to share, it’s best to keep the leftovers away from your furry friends. Ingredients like onions and certain seasonings can be harmful to pets. If you’re looking to share a special treat, consider setting aside a portion before adding any spices or seasonings that may not be safe for them.

Delicious Biscuit Breakfast Casserole for Cozy Mornings
Ingredients
Equipment
Method
- Preheat your oven to 400°F (200°C) and prepare a 9x13 inch baking pan by greasing it with cooking spray or butter.
- In a large sauté pan, add the Italian ground sausage over medium heat. Break it into crumbles and cook for about 5-7 minutes.
- Open the canned Grand biscuits and cut each biscuit into eight equal pieces. Spread them in a single layer across the bottom of your prepared baking pan.
- Evenly distribute the cooked sausage over the layer of biscuits in the pan. Then, sprinkle half a cup of both shredded cheddar and mozzarella cheese on top.
- In a separate bowl, whisk together the large eggs, milk, salt, and black pepper until combined. Pour this mixture evenly over the layered biscuits and sausage.
- Top the casserole with the remaining shredded cheddar and mozzarella cheese.
- Bake for 25-35 minutes until the eggs are set and the top is golden brown.
- Once baked, remove the casserole from the oven and let it sit for about 5 minutes before slicing and serving.
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